Los Angeles Rams quarterback Matthew Stafford has a difficult matchup in Week 5 (Thursday at 8:15 p.m. ET), up against the San Francisco 49ers. The 49ers are allowing the sixth-fewest passing yards in the NFL, 165 per game.
Stafford has posted 1,114 passing yards (278.5 per game) this year, going 92-for-136 (67.6%) with eight touchdown passes and two interceptions. Also, Stafford has run for -4 rushing yards (-1.0 per game) on 10 carries.
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Stafford vs. the 49ers
- Stafford vs the 49ers (since 2021): 6 GP / 257.7 PASS YPG / 10 PASS TD
- San Francisco has not allowed an opposing quarterback to throw for 300 or more passing yards in an outing this year.
- The 49ers have given up one or more passing touchdowns to three opposing quarterbacks this season.
- San Francisco has given up at least two passing touchdowns to one quarterback in 2025.
- The 49ers have allowed one opposing player to throw for three or more TD passes in an outing this season.
- The 49ers surrender 165 passing yards per game, the NFL's sixth-ranked pass defense this season.
- The 49ers' defense ranks seventh in the league by conceding 1.3 passing touchdowns per game to their opponents (five total passing TDs).
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Stafford Passing Insights
- Stafford has gone over his passing yards total three times this season (75.0%).
- The Rams pass on 56.1% of their plays and run on 43.9%. They are 13th in NFL action in points scored.
- With 136 attempts for 1,114 passing yards, Stafford is fifth in league action with 8.2 yards per attempt.
- Stafford has thrown for a touchdown in all four games this year, with more than one TD pass three times.
- He has scored eight of his team's 11 offensive touchdowns this season (72.7%).
- Stafford accounts for 51.3% of his team's red zone plays, with 20 of his total 136 passing attempts inside the opponent's 20-yard line.
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Stafford's Recent Performance
| Opponent | Date | Week | Passing Stats | Rushing Stats |
|---|---|---|---|---|
| vs. Colts | 9/28/2025 | Week 4 | 29-for-41 / 375 YDS / 3 TDs / 0 INTs | 4 ATT / 4 YDS / 0 TDs |
| vs. Eagles | 9/21/2025 | Week 3 | 19-for-33 / 196 YDS / 2 TDs / 1 INT | 0 ATT / 0 YDS / 0 TDs |
| vs. Titans | 9/14/2025 | Week 2 | 23-for-33 / 298 YDS / 2 TDs / 1 INT | 2 ATT / -6 YDS / 0 TDs |
| vs. Texans | 9/7/2025 | Week 1 | 21-for-29 / 245 YDS / 1 TD / 0 INTs | 4 ATT / -2 YDS / 0 TDs |